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Trafficking of glucose, lactate, and amyloid-beta from the inferior colliculus through perivascular routes
Journal of Cerebral Blood Flow & Metabolism, 10/14/09
Ball KK et al. – Efflux of extracellular glucose, lactate, and A–beta into perivascular fluid pathways is a normal route for clearance of material from the inferior colliculus that contributes to underestimates of brain energetics. Convergence of 'watershed' drainage to common pathways may facilitate perivascular amyloid plaque formation and pathway obstruction in Alzheimer's disease.
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