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Unique Molecular Characteristics of Pediatric Myxopapillary Ependymoma
Brain Pathology, 10/02/09
Barton VN et al. – Spinal and intracranial EPN generally expressed weak or focal staining. MEPN manifests unique gene and protein expression patterns compared to other EPNs. Aberrant expression of HOXB13 suggests possible recapitulation of developmental pathways in MEPN tumorigenesis. PDGFR–alpha may be a potential therapeutic target in recurrent MEPN.
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