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See Latest ArticlesReducing Abuse Liability of GABAA/Benzodiazepine Ligands via Selective Partial-Agonist Efficacy at alpha1 and alpha2/3 Subtypes
Journal of Pharmacology and Experimental Therapeutics, 10/14/09
Ator NA et al. – Elimination of efficacy at the alpha1 subtype of the GABA/benzodiazepine receptor is not sufficient to eliminate abuse liability but may do so when coupled with reduced alpha2/3 subtype efficacy.
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