Neurology Medical News about Neuralgia Pain Sensory Functions

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Evaluation of Symptom Heterogeneity in Neuropathic Pain Using Assessments of Sensory Functions
Neurotherapeutics, 10/05/09

Arning K et al. – By using a battery of several standardized quantitative sensory tests, the characteristic profile of sensory symptoms can be elucidated in each patient. Moreover, in questionnaires the verbal descriptors can depict the quality and intensity of the individual pain. The approach of classifying and subgrouping patients with neuropathic pain on the basis of symptoms or signs opens up new possibilities for stratifying patients in clinical trials. First, in clinical proof–of–concept trials the study population can be enriched prospectively on the basis of entry criteria defined a priori. This enrichment with patients who potentially require a specific treatment should increase the likelihood for positive trial outcomes. Second, in clinical practice it becomes possible to establish an individualized therapy – that is, to identify the particular patients who require a specific treatment option.

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Rectal Sensory Threshold for Pain is a Diagnostic Marker of Irritable Bowel Syndrome and Functional Abdominal Pain in Children
The Journal of Pediatrics, 10/08/09 Relevance Score: 82%

Neuropathic pain: Peripheral and central mechanisms
European Journal of Pain, 11/12/09 Relevance Score: 81%

Evidence of descending inhibition deficits in atypical but not classical trigeminal neuralgia
Pain, 10/20/09 Relevance Score: 81%

Gliopathic Pain: When Satellite Glial Cells Go Bad
The Neuroscientist, 10/16/09 Relevance Score: 81%

Persistent sensory dysfunction in pain-free herniotomy
Acta Anaesthesiologica Scandinavica, 10/16/09 Relevance Score: 81%