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Neurotrophins in the Cerebrospinal Fluid of Patient Cohorts With Neuropathic Pain, Nociceptive Pain, or Normal Pressure Hydrocephalus
The Clinical Journal of Pain, 09/29/09
Capelle H–H et al. – The authors did not detect any difference between patients with neuropathic versus nociceptive pain and nonpainful controls for spinal CNTF, BDNF, and NGF levels. Lower GDNF concentrations found in neuropathic pain patients might be associated with increased receptor expression. Possible alterations of neurotrophic factors at spinal relays, however, might not be reflected adequately in changes of CSF concentrations.
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