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Effect of Telmisartan on Functional Outcome, Recurrence, and Blood Pressure in Patients With Acute Mild Ischemic Stroke. A PRoFESS Subgroup Analysis
Stroke, 09/28/09

Bath PMW et al. – Treatment with telmisartan in 1360 patients with acute mild ischemic stroke and mildly elevated BP appeared to be safe with no excess in adverse events, was not associated with a significant effect on functional dependency, death, or recurrence, and modestly lowered BP.

Exclusive Author Commentary
Philip M. W. Bath, 09/28/09

The data suggest that moderate lowering of BP is at least safe in patients with recent mild ischaemic stroke. But it will take larger ongoing trials (e.g. ENOS, SCAST) to define effects on efficacy. ENOS: http://www.enos.ac.uk/ SCAST: http://www.scast.no/

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Stroke Associated with Atrial Fibrillation - Incidence and Early Outcomes in the North Dublin Population Stroke Study
Cerebrovascular Diseases, 11/19/09 Relevance Score: 93%

Differences Between Ischemic Stroke Subtypes in Vascular Outcomes Support a Distinct Lacunar Ischemic Stroke Arteriopathy. A Prospective, Hospital-Based Study
Stroke, 11/09/09 Relevance Score: 93%

Oral anticoagulant therapy safely prevented stroke in older patients with atrial fibrillation
Evidence-Based Medicine, 10/26/09 Relevance Score: 93%

Advancing the hypothesis that geographic variations in risk factors contribute relatively little to observed geographic variations in heart disease and stroke mortality
Preventive Medicine, 10/16/09 Relevance Score: 93%

Prevention and management of stroke in very elderly patients
The Lancet Neurology, 10/15/09 Relevance Score: 93%