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Multiple roles of HDAC inhibition in neurodegenerative conditions
Trends in Neurosciences, 09/25/09

Chuang DM et al. – HDAC inhibitors have neuroprotective, neurotrophic and anti–inflammatory properties; improvements in neurological performance, learning/memory and other disease phenotypes are frequently seen in these models. The authors discuss the targets and mechanisms underlying these effects of HDAC inhibition and comment on the potential for some HDAC inhibitors to prove clinically effective in the treatment of neurodegenerative disorders.

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The Antiapoptotic Activity of Melatonin in Neurodegenerative Diseases
CNS Neuroscience & Therapeutics, 11/11/09 Relevance Score: 71%

Potential Mechanisms Involved in the Prevention of Neurodegenerative Diseases by Lithium
CNS Neuroscience & Therapeutics, 11/11/09 Relevance Score: 68%

Protein-misfolding in neurodegenerative disease
The Internet Journal of Neurology, 11/04/09 Relevance Score: 67%

FUS-Immunoreactive Intranuclear Inclusions in Neurodegenerative Disease
Brain Pathology, 10/16/09 Relevance Score: 67%

Imaging Cerebral Blood Flow in the Cognitively Normal Aging Brain with Arterial Spin Labeling: Implications for Imaging of Neurodegenerative Disease
Journal of Neuroimaging, 10/13/09 Relevance Score: 67%