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Voxel-based morphometry of sporadic epileptic patients with mesiotemporal sclerosis
Epilepsia, 09/24/09
Labate A et al. – In both rTLE and mTLE, VBM shows GM reductions not confined to the hippocampus involving mainly the thalamus bilaterally. This finding together with the lack of significant GM differences between the two TLE groups supports the hypothesis that mTLE and rTLE might lie along a biologic continuum, suggesting a pathophysiologic role of the thalamus in partial epilepsy.
Dr. Angelo Labate, 09/25/09
| This is an interesting finding because, together with reports of MRI evidence of hippocampal sclerosis (Hs) in epilepsy patients with good seizure control, may give a different interpretation of the significance of Hs. |
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