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Brain atrophy and lesion load measures over one year relate to clinical status after 6 years in patients with clinically isolated syndromes
Journal of Neurology, Neurosurgery, and Psychiatry , 09/23/09
Di Filippo M et al. – The findings confirm that brain atrophy occurs during the earliest phases of MS and suggest that one–year longitudinal measures of MRI change, if considered together with baseline MRI variables, might help to predict clinical status six years after the first demyelinating event in CIS patients, better than measurements such as lesion or brain volumes on baseline MRI alone.
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