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Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449
New England Journal of Medicine, 09/17/09
Rudin CM et al. – Molecular analyses of tumor specimens obtained before treatment suggested that there was activation of the hedgehog pathway, with loss of heterozygosity and somatic mutation of the gene encoding patched homologue 1 (PTCH1), a key negative regulator of hedgehog signaling.
Today in Neurologic Oncology...keeping you current
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Medulloblastoma in childhood: revisiting intrathecal therapy in infants and children
Cancer Chemotherapy and Pharmacology, 10/29/09
Reirradiation for progressive brain metastases
Journal of Cancer Research and Therapeutics, 10/27/09
Critical appraisal of temozolomide formulations in the treatment of primary brain tumors: patient considerations
Cancer Management and Research, 11/05/09
Today in Pediatric Neurology...keeping you current
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Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and Adolescents
JAMA, 10/29/09
Imaging of Back Pain in Children
American Journal of Neuroradiology, 11/23/09
Neonatal seizures
Current Treatment Options in Neurology, 10/28/09
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