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Nitric Oxide-Induced Changes in Endothelial Expression of Phosphodiesterases 2, 3, and 5
Headache: The Journal of Head and Face Pain, 09/17/09
Schankin CJ et al. – Long–term NO stimulation modulated PDE3 and PDE5 mRNA expression in endothelial cells. However, PDE3 and PDE5 protein levels were unaffected by NO. The presence of PDE3 or PDE5 in endothelial cells indicates that selective inhibitors may have functional effects in such cells. A complex interaction of cGMP and cAMP in response to NO administration may take place if the mRNA translates into active protein. Whether or not this plays a role in the headache mechanisms remains to be investigated.
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25-Hydroxyvitamin D levels and cognitive performance and decline in elderly men
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Today in Headache...keeping you current
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Contrast Echocardiography and Migraine in Divers with Patent Foramen Ovale
Canadian Journal of Neurological Sciences, 11/25/09
Efficacy of Biofeedback in the Treatment of Migraine and Tension Type Headaches
Pain Physician, 11/25/09
Paroxysmal head pain with backward radiation: will epicrania fugax go in the opposite direction?
The Journal of Headache and Pain, 11/25/09
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