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Agents and mechanisms of toxic myopathy
Current Opinion in Neurology, 09/29/09
Kuncl RW – A principled approach to the diagnosis of toxic myopathies, based on the consideration of currently known pathophysiologic mechanisms, biopsy pathology, the characteristic clearance properties of creatine kinase, the time course of muscle fiber regeneration, drug challenge/de–challenge/re–challenge, and differential diagnoses, rather than on mere temporal association, will reduce the healthcare costs of common diagnostic error.
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