Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Doctors and the DEA Free full text
Top Ten Searches
parkinson's neuritis neuralgia myasthenia gravis lactic acidosis ataxia seizure tinnitus migraine hypotoniaYour Article Summary
See Latest ArticlesCurrent Alzheimer's disease clinical trials: Methods and placebo outcomes
Alzheimer's & Dementia , 09/24/09
Schneider LS et al. – Inclusion criteria are essentially similar to earlier 6–month and 12–month trials in which cholinesterase inhibitors were not allowed, as were mean ADAS–cog rates of change. Yet increasing variability and relatively little change overall in the ADAS–cog placebo groups, eg, about 25% of patients do not worsen by more than 1 point, might make it more unlikely than previously assumed that a modestly effective drug can be reliably recognized, especially when the drug might work only to attenuate decline in function and not to improve function. These observations would be strengthened by pooling individual trials data, and pharmaceutical sponsors should participate in such efforts.
Related Articles
Does Diabetes Speed Up Memory Loss In Alzheimers Disease?
ScienceDaily, 10/28/09
Relevance Score: 71%
High Blood Pressure Likely in Alzheimers Offspring
MedLinePlus, 11/04/09
Relevance Score: 70%
Activated astrocytes: a therapeutic target in Alzheimer's disease?
Expert Review of Neurotherapeutics, 11/19/09
Relevance Score: 69%
Protective Role For Copper In Alzheimers Disease
ScienceDaily, 10/14/09
Relevance Score: 69%
All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease
Expert Review of Neurotherapeutics, 11/19/09
Relevance Score: 68%
Today in Dementia...keeping you current
Receive free subspecialty "5-minute updates" via email
Overgenerality of Autobiographical Memory in People with Amnestic Mild Cognitive Impairment and Early Alzheimer's Disease
Archives of Clinical Neurospsychology, 12/05/09
MRI Substudy Participation in Alzheimer Disease (AD) Clinical Trials: Baseline Comparability of a Substudy Sample to Entire Study Population
Alzheimer Disease & Associated Disorders , 12/04/09
A Case Series of Epilepsy-derived Memory Impairment Resembling Alzheimer Disease
Alzheimer Disease & Associated Disorders , 12/04/09
Sponsor
Article Search
Sponsor