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Placebo-corrected efficacy of modern antiepileptic drugs for refractory epilepsy: Systematic review and meta-analysis
Epilepsia, 09/18/09
Beyenburg S et al. – Although the presence of moderate heterogeneity may reduce the validity of the results and limit generalizations from the findings, the authors conclude that the placebo–corrected efficacy of adjunctive treatment with modern AEDs is disappointingly small and suggest that better strategies of finding drugs are needed for refractory epilepsy, which is a major public health problem.
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