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Paulson OB et al. – On the basis of earlier studies, the authors take into consideration the functional recruitment of capillaries and attempt to accommodate the cerebral tissue's increased demand for glucose supply during neural activation with recent evidence supporting a key function for astrocytes in rCBF regulation.


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OB Paulson, 10/16/09

In this review, the authors argue that the key mechanism responsible for the regional cerebral blood flow (rCBF) increase during functional activation is a tight coupling between rCBF and glucose metabolism.

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