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Sleep and Neuromuscular Disease
Seminars in Neurology, 09/25/09

Nicolle MW – Inadequate ventilation underlies many sleep disorders, and sleep–related disorders may presage daytime ventilatory disorders with disease progression. Involvement of the central or peripheral nervous system, or both, may disrupt sleep, with the relative contribution of each depending on the specific disorder. The pertinent anatomy, physiology, and clinical features of sleep disorders in neuromuscular diseases and a basic approach to their assessment is discussed. Specific neuromuscular disorders in which sleep is commonly affected are reviewed and the principles of management of sleep disorders summarized.

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