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Cliniconeuropathologic correlates of human immunodeficiency virus in the era of antiretroviral therapy
Journal of Neurovirology, 09/10/09
Everall I et al. – The frequency of HIV brain pathology was lower than previous pre–antiretroviral reports, and was predicted by lower nadir CD4 and higher plasma viral load. Noninfectious pathologies and minimal changes correlated with HIV–associated neurocognitive disorder, suggesting a shift in pathogenesis from florid HIV replication to other, diverse mechanisms.
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