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A comparative study of LRRK2, PINK1 and genetically undefined familial Parkinson disease
Journal of Neurology, Neurosurgery, and Psychiatry , 09/09/09
Nishioka K et al. – Clinical differences between LRRK2, PINK1 and genetically undefined familial PD appear more pronounced than previously appreciated, and may prove useful in clinical practice. As future therapies are targeted to specific protein abnormalities, identifying the genetic causes and associated clinical and pathologic features will determine diagnosis, preventative medicine and drug intervention strategies.
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