Neurology Medical News about spinal cord injury pain

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Mechanisms of spinal cord injury pain: from animal to man
Scandinavian Journal of Pain, 09/02/09

Finnerup NB – Quantitative sensory testing, imaging, and pharmacological trials represent tools that may help understanding the mechanisms involved in SCI neuropathic pain in humans and to understand why some patients develop pain in body parts that have lost their afferent input while others with the same degree of deafferentation do not develop such pain. There seem to be a correlation between at–level evoked pain and spontaneous below–level pain and larger grey matter lesions at the rostral end of the spinal lesion in patients with below–level pain compared to pain–free patients suggesting a role for neuronal hyperexcitability at the lesion site for below–level pain. Changes in thalamus and cortical areas are likely to play a role in combination with spinal mechanisms.

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Association of depression and pain interference with disease-management self-efficacy in community-dwelling individuals with spinal cord injury
Journal of Rehabilitation Medicine, 11/10/09 Relevance Score: 90%

Pain Symptom Profiles in Persons with Spinal Cord Injury
Pain Medicine, 10/14/09 Relevance Score: 90%

Peripheral and central sensitization in remote spinal cord regions contribute to central neuropathic pain after spinal cord injury
Pain, 10/26/09 Relevance Score: 89%

Brain Anatomy Changes Associated with Persistent Neuropathic Pain Following Spinal Cord Injury
Cerebral Cortex, 10/13/09 Relevance Score: 89%

Reliability and validity of the International Spinal Cord Injury Basic Pain Data Set items as self-report measures
Spinal Cord, 10/02/09 Relevance Score: 89%