Neurology Medical News about zonisamide; Parkinson’s disease

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Review: A review of the use of zonisamide in Parkinson’s disease
Therapeutic Advances in Neurological Disorders, 09/04/09

Bermejo PE et al. – This antiepileptic drug has been used in Japan for more than 15 years and so it is expected that it will be safe and well tolerated in patients with Parkinson’s disease. However, the pharmacological mechanisms of the antiparkinsonian actions of zonisamide remain unclear and more basic investigation is warranted. The aim of this paper is to review the structure, mechanisms of action, pharmacokinetics and antiparkinsonian action of zonisamide.

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