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Report on mutation in exon 15 of the APC gene in a case of brain metastasis
Journal of Neuro-Oncology, 08/31/09
Pecina–Slaus N et al. – The study analyzes exon 15 of the adenomatous polyposis coli gene (APC) in a 49–year–old male patient with brain metastasis. The primary site was lung carcinoma. PCR method and direct DNA sequencing of the metastasis and autologous lymphocyte samples identified the presence of a somatic mutation.
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