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Effects of overnight sleep restriction on brain chemistry and mood in women with unipolar depression and healthy controls
Journal of Psychiatry & Neuroscience , 09/01/09
Bernier D et al. – Sleep restriction altered levels of pontine tCr and prefrontal Cho in both groups combined, suggesting effects on phospholipid and creatine metabolism. Baseline levels of pontine Cho were linked to subsequent mood responses to sleep loss, suggesting a role for pontine phospholipid metabolism in mood effects of sleep restriction.
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