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Clinical outcome of concomitant chemoradiotherapy followed by adjuvant temozolomide therapy for glioblastaomas: Single-center experience
Clinical Neurology and Neurosurgery, 09/02/09
Jeon HJ et al. – The median and 2-year survival outcomes in this study are comparable to the previous reports.
Methods- 79 patients with pathologically-confirmed glioblastomas were treated with radiotherapy combined with temozolomide, followed by adjuvant temozolomide
- Median OS was 18.3 mos and the TTP was 6.7 mos
- 1-y and 2-y survival rates were 70.1% and 37.1%, respectively
- The patients with a post-operative KPS > 80 showed more prolonged survival than those who had a KPS < 80 (23.1 mos vs. 13.4 mos)
- Hematologic toxicity occurred in 8.8% of patients
Today in Neuro/Psych pharmacology...keeping you current
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Effects of Methylphenidate on Cerebral Glucose Metabolism in Patients With Impaired Consciousness After Acquired Brain Injury
Clinical Neuropharmacology, 12/05/09
Gabapentin Enacarbil in Restless Legs Syndrome: A Phase 2b, 2-Week, Randomized, Double-Blind, Placebo-Controlled Trial
Clinical Neuropharmacology, 12/05/09
Inhibition of long-term potentiation by valproic acid through modulation of cyclic AMP
Epilepsia, 12/05/09
Today in Neurologic Oncology...keeping you current
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Antiepileptics in brain metastases: safety, efficacy and impact on life expectancy
Journal of Neuro-Oncology, 12/04/09
High-dose chemotherapy and autologous stem cell rescue for atypical teratoid/rhabdoid tumor of the central nervous system
Journal of Neuro-Oncology, 12/04/09
Seizure risk in brain tumor patients with conversion to generic levetiracetam
Journal of Neuro-Oncology, 12/04/09
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