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C-nociceptors sensitized to cold in a patient with small-fiber neuropathy and cold allodynia
Pain, 08/27/09
Serra J et al. – These findings provide the first direct evidence in human of abnormal peripheral nociceptor behavior potentially responsible for cold allodynia. The responsiveness of C–nociceptors to menthol suggests an abnormal expression or function of TRPM8 channels in this patient with a small–fiber polyneuropathy.
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