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See Latest ArticlesLimitations in a frataxin knockdown cell model for Friedreich ataxia in a high-throughput drug screen
BMC Neurology, 08/25/09
Calmels N et al. – Although no active hit has been identified, the present study demonstrates the feasibility of using a cell–based approach to HTS for FRDA. Furthermore, it highlights the difficulty in the development of a stable frataxin–deficient cell model, an essential condition for productive HTS in the future.
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