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See Latest ArticlesApoptosis induction by different local anaesthetics in a neuroblastoma cell line
British Journal of Anesthesia, 08/28/09
Werdehausen R et al. – All commonly used local anaesthetics induce neuronal apoptosis in clinically used concentrations. The neurotoxicity correlates with lipid solubility and thus with the conduction blocking potency of the local anaesthetic, but is independent of the chemical class (ester/amide).
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