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Antiepileptic drugs abolish ictal but not interictal epileptiform discharges in vitro
Epilepsia, 08/28/09
D'Antuono M et al. – The AED ability to control epileptiform synchronization in vitro depends mainly on activity–dependent characteristics such as discharge duration. The data are in keeping with clinical evidence indicating that interictal activity is unaffected by AED levels that are effective to stop seizures.
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