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See Latest ArticlesGrammar improvement following deep brain stimulation of the subthalamic and the pedunculopontine nuclei in advanced Parkinson's disease: A pilot study
Parkinsonism & Related Disorders, 08/21/09
Zanini S et al. – Findings replicate previous observations on the subthalamic (STN) and provide the rationale for further investigation of the role of the pedunculopontine (PPN) in processing linguistic grammar.
Methods- Study of 5 advanced Parkinson's disease pts who had combined deep brain stimulation (STN + PPN)
- Overall cognitive profile did not change
- In contrast, stimulation of the STN, and also the PPN, when STN switched off showed an interesting trend towards reduction of ungrammatical errors
- Ungrammatical errors: particularly substitution of free and inflectional morphemes
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