Neurology Medical News about Parkinson's disease, Tinetti gait assessment, physiotherapy, mortality

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5. Doctors and the DEA Free full text

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Gray WK et al. – Results suggest a link between reduced physical function and an increased mortality risk in Parkinson's disease (PD) populations.

Methods

Retrospective correlation study for cohort of 109 PD pts
Primary aim: determination of whether a battery of physical function measures in a PD pt cohort predicted mortality status at 7-yr follow-up
Secondary aims: report of which specific tests were most useful and whether PD phenotype was a predictor
Baseline physiotherapy assessment of gait, balance, posture, muscle strength, and ability to change postural set
Comparison of mortality status at 7-yr follow-up and baseline physical assessment tests

Results

Statistically significant physical predictors of mortality at 7-yr follow-up:
Tinetti gait and balance scores
UPDRS scores
10-m walk test (time, velocity, and number of strides)
Posture in standing, lying to sitting, sitting to standing, getting up from floor assessments
Time to ascend and descend 4 steps
Significant nonphysical predictors of mortality: age, sex, and MMSE
Cox regression survival model constructed with age, sex, and Tinetti gait score as independent predictors of mortality

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