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Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis
Annals of Neurology , 08/24/09
Gadjanski I et al. – N–type VDCCs play an important role in inflammation–induced axon degeneration via two mechanisms: First, they directly mediate toxic Ca2+ influx into the axons; and second, they contribute to macrophage/microglia function, thereby promoting secondary axonal damage.
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