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Analysis of genetic variants of phosphodiesterase 11A (PDE11A) in acromegalic patients
European Journal of Endocrinology, 08/12/09

Lania A et al. – The study first demonstrated the presence of PDE11A variants in a subset of acromegalic patients, that was only slightly more frequent than in controls. The normal expression of PDE11A in the majority of tumor tissues together with the lack of significant clinical phenotype suggest that these variants might only marginally contribute to the development of somatotropinomas.

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Prevalence of mental disorders in acromegaly: a cross-sectional study in 81 acromegalic patients
Clinical Endocrinology, 10/15/09 Relevance Score: 84%

Diffusing Lung Capacity of Carbon Monoxide/Alveolar Volume as an Index for Evaluating Diffusing Capacity of the Acromegalic Lung
The Endocrinologist, 11/17/09 Relevance Score: 83%

The Efficacy of Octreotide LAR as Firstline Therapy for Patients with Newly Diagnosed Acromegaly is Independent of Tumor Extension: Predictive Factors of Tumor and Biochemical Response
Hormone and Metabolic Research, 10/06/09 Relevance Score: 82%

Comparative Evaluation of Optical Colonoscopy and Multidetector Computerized Tomographic Colonoscopy for Detection of Colonic Polyps in Acromegaly: A Preliminary Study
The Endocrinologist, 11/17/09 Relevance Score: 80%

Discordant Nadir GH After Oral Glucose and IGF-I Levels on Treated Acromegaly: Refining the Biochemical Markers of Mild Disease Activity
Hormone and Metabolic Research, 10/06/09 Relevance Score: 80%