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Seizures increase cell proliferation in the dentate gyrus by shortening progenitor cell-cycle length
Epilepsia, 08/21/09
Varodayan FP et al. – The sustained increase in dentate gyrus cell proliferation following SE provides a large pool of immature dentate granule cells prior to development of spontaneous seizures. A decrease in cell–cycle length of dentate gyrus progenitors is at least partially responsible for increased numbers of newborn cells following SE.
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