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Reevaluating the mechanisms of focal ictogenesis: The role of low-voltage fast activity
Epilepsia, 08/24/09
De Curtis M et al. – The findings challenge the classical theory that proposes an increment of excitation and/or a reduction of inhibition as a cause for the transition to seizure in focal epilepsies. A new definition of ictogenesis mechanisms, as herewith hypothesized, might possibly help to develop new therapeutic strategies for focal epilepsies.
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