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See Latest ArticlesMidbrain hyperechogenicity in idiopathic REM sleep behavior disorder
Movement Disorders, 08/04/09
Stockner H et al. – The first case-control study assessing midbrain echogenicity in a large idiopathic RBD (iRBD) cohort vs age- and sex-matched healthy controls finds that increased prevalence of hyperechogenicity in pt subgroup with a priori increased risk for Parkinson's disease (PD) supports the potential role of hyperechogenicity as a risk marker for PD. Prospective follow-up of this iRBD cohort must establish if pts with midbrain hyperechogenicity will develop clinically defined PD.
Methods- Study of midbrain echogenicity by transcranial sonography (TCS) in pts with iRBD
- Comparison of findings with healthy controls
- TCS in 55 iRBD pts and in 165 age and sex-matched controls
- Area of echogenicity significantly increased in SN region for iRBD group vs controls
- SN hyperechogenicity for ~19 iRBD pts (37.3%) vs 16 controls (10.7%)
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