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See Latest ArticlesMonitoring of acromegaly: what should be performed when GH and IGF-1 levels are discrepant
Clinical Endocrinology, 07/13/09
Freda PU et al. - Monitoring of a patient with acromegaly requires periodic evaluation of levels of GH and IGF-1, the biochemical markers of this disease. Although the results of these two tests are usually concordant, they can be discrepant and how to proceed when they are can be a challenging clinical problem. In some cases, IGF-1 levels are normal yet GH suppression after oral glucose is abnormal; this pattern may be due to persistent GH dysregulation despite remission.
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