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MR Spectroscopy Indicates Diffuse Multiple Sclerosis Activity During Remission
Journal of Neurology, Neurosurgery, and Psychiatry , 07/10/09
Kirov I et al. - The absence of early tissue atrophy and apparent axonal dysfunction (NAA loss) in these RR MS patients suggests that both are preceded by diffuse glial proliferation (astrogliosis), as well as possible inflammation, de- and re-myelination reflected by elevated mI, Cho and Cr, even during clinical remission and despite immunomodulatory treatment.
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