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Marazziti D et al. - Although the main biological hypothesis on the pathophysiology of obsessive-compulsive disorder (OCD) is centered on the serotonin system, indications are available that other neurotransmitters, and even second messengers, particularly the cyclic adenosine monophosphate (cAMP) signaling, may be involved, though effective data are few. These findings suggest the presence of supersensitive beta-adrenergic receptors in platelets of OCD patients.

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