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The Deep Brain Stimulation of the Pedunculopontine Tegmental Nucleus
Neuromodulation, 07/01/09

Mazzone P et al. - The surgical targeting of the pedunculopontine tegmental nucleus requires a careful adaptation of the traditional stereotactic approaches owing to the high variability of brainstem anatomy from one patient to another. The insertion of the leads in the pedunculopontine tegmental nucleus as well as their activation did not appear to induce serious adverse effects. The correct positioning of stimulating electrodes in pontine structures such as the pedunculopontine nucleus may be ascertained not only through neuroimaging techniques but also through clinical neurophysiology.

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