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Operative techniques for gliomas and the value of extent of resection
Neurotherapeutics, 07/01/09

Sanai N et al. – A review of the operative techniques for gliomas and the value of extent of resection reports that, despite persistent limitations in the quality of available studies, a more extensive surgical resection is associated with longer life expectancy for both low-grade and high-grade gliomas.

• Review of operative techniques and value of extent of resection for gliomas
• Analysis of modern intraoperative mapping techniques
• Assessment of every major clinical publication since 1990 on the role of resection extent in glioma outcome

• Cortical language mapping: safe and efficient adjunct to optimize tumor resection while preserving essential language sites, even in the setting of negative mapping data
• Unclear value of maximizing glioma resections; no general consensus for efficacy of the extent of glioma resection in improving pt outcome
• Clear importance of resection in obtaining tissue diagnosis and alleviating symptoms
• Lack of class I evidence for assessing influence of extent of resection

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