Neurology Medical News about gliomas;operative techniques;extent of resection

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Operative techniques for gliomas and the value of extent of resection
Neurotherapeutics, 07/01/09

Sanai N et al. – A review of the operative techniques for gliomas and the value of extent of resection reports that, despite persistent limitations in the quality of available studies, a more extensive surgical resection is associated with longer life expectancy for both low-grade and high-grade gliomas.

Methods

Review of operative techniques and value of extent of resection for gliomas
Analysis of modern intraoperative mapping techniques
Assessment of every major clinical publication since 1990 on the role of resection extent in glioma outcome

Results

Cortical language mapping: safe and efficient adjunct to optimize tumor resection while preserving essential language sites, even in the setting of negative mapping data
Unclear value of maximizing glioma resections; no general consensus for efficacy of the extent of glioma resection in improving pt outcome
Clear importance of resection in obtaining tissue diagnosis and alleviating symptoms
Lack of class I evidence for assessing influence of extent of resection

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