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Nocentini U et al. - The presence of an altered pattern of anger, unrelated to the clinical severity of MS, suggests that anger is not an emotional reaction to disease stress. An alteration of anger mechanisms might be a direct consequence of the demyelination of the connections among the amygdale, the basal ganglia and the medial prefrontal cortex.

Exclusive Author Commentary
Ugo Nocentini, 07/07/09

The study of the neuropsychiatric features of Multiple Sclerosis' patients open new scenarios not only for those interested in the care of this illness, but also for the comprehension of the causes of neuropsychiatric and emotional disturbances. In this framework, the processing of emotions and their anatomical and functional correlates can give an important contribution.

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