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Oxidative stress in SEPN1-related myopathy: From pathophysiology to treatment
Annals of Neurology , 06/30/09

Arbogast S et al. - SelN plays a key role in redox homeostasis and human cell protection against oxidative stress. Oxidative/nitrosative stress is a primary pathogenic mechanism in SEPN1-RM, which can be effectively targeted ex vivo by antioxidants. These findings pave the way to SEPN1-RM treatment, which would represent a first specific pharmacological treatment for a congenital myopathy.

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Inflammatory myopathies
Zeitschrift für Rheumatologie, 10/07/09 Relevance Score: 93%

Muscle carnitine deficiency: adult onset lipid storage myopathy with sensory neuropathy
Neurological Sciences, 10/07/09 Relevance Score: 89%

Vaccines as a trigger for myopathies
Lupus, 11/16/09 Relevance Score: 88%

Stroke in Myopathies
Cerebrovascular Diseases, 11/18/09 Relevance Score: 87%

Immune-mediated necrotizing myopathy associated with statins
Muscle & Nerve, 10/12/09 Relevance Score: 87%