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Lacosamide: A New Approach to Target Voltage-Gated Sodium Currents in Epileptic Disorders
CNS Drugs, 06/26/09
Curia G et al. - Recent data indicate that lacosamide shares a similar mechanism. When compared with other AEDs, lacosamide has the unique ability to interact with sodium channel slow inactivation without affecting fast inactivation. This article reviews these findings and discusses their relevance within the context of neuronal activity seen during epileptiform discharges generated by limbic neuronal networks in the presence of chemical convulsants.
Today in Neuro/Psych pharmacology...keeping you current
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Escitalopram and Venlafaxine for the Prophylaxis of Migraine Headache Without Mood Disorders
Clinical Neuropharmacology, 10/02/09
Nortriptyline and gabapentin, alone and in combination for neuropathic pain: a double-blind, randomised controlled crossover trial
The Lancet, 10/13/09
Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and Adolescents
JAMA, 10/29/09
Today in Seizure...keeping you current
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Risk factors for valproic acid resistance in childhood absence epilepsy
Seizure - European Journal of Epilepsy, 10/21/09
The teratogenic risk of antiepileptic drug polytherapy
Epilepsia, 10/13/09
Neonatal seizures
Current Treatment Options in Neurology, 10/28/09
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