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Sensitivity of conventional memory tests in multiple sclerosis: comparing the Rao Brief Repeatable Neuropsychological Battery and the Minimal Assessment of Cognitive Function in MS
Multiple Sclerosis, 06/29/09

Strober L et al. – The Rao Brief Repeatable Neuropsychological Battery (BRNB) and Minimal Assessment of Cognitive Function in Multiple Sclerosis (MACFIMS). have comparable sensitivity among pts with multiple sclerosis (MS). Although the sensitivity of the auditory/verbal memory tests is similar, BVMTR appears more sensitive than the 10/36.

• Study of the different memory tests of the BRNB and MACFIMS
• BRNB: Selective Reminding Test (SRT) and 10/36 Spatial Recall Test (10/36)
• MACFIMS: California Verbal Learning Test, Second Edition (CVLT2) and Brief Visuospatial Memory Test, Revised (BVMTR)
• Comparison of test sensitivity and their respective batteries in 65 MS pts and 46 demographically matched controls

• BRNB and MACFIMS comparable in overall sensitivity to disease status
• BVMTR showed greater discriminative validity than 10/36
• CVLT2 and SRT comparable in sensitivity
• SDMT most sensitive NP test across both batteries

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