Your Article Summary
See Latest ArticlesPrognostic factors of subthalamic stimulation in Parkinson’s disease: A comparative study between short- and long-term effects
Stereotactic and Functional Neurosurgery , 06/30/09
Tsaia ST et al. – Prognostic factors for subthalamic nucleus deep brain stimulation (STN-DBS) benefit differed for short- and long-term follow-ups. Good prognostic factors for long-term STN-DBS for PD pts were good cognitive function and tremor dominance. Poor prognostic factors were related to older age and non-dopaminergic-responsive axial disability.
Methods- Study of prognostic factors for short- and long-term effects of STN-DBS
- Bilateral STN-DBS for 36 PD
- Clinical evaluations 1 mo before and 3 mo after surgery, with additional follow-up examinations for a mean of 31.3 mo
- Trend for long-term STN-DBS-induced improvements in Unified Parkinson's Disease Rating Scale (UPDRS) part II and part III measures greater in younger pts
- Preoperative levodopa responsiveness only led to consistent UPDRS part III improvement from STN-DBS at 3 mo; this predictive value did not exist in the long term
- Preoperative levodopa response of tremor and axial symptoms in motor disability predicted long-term DBS effect only
- Preoperative cognitive function positively correlated with postoperative improvement from DBS in UPDRS part III during long-term follow-up only
Related Articles
Stimulation-Induced Dyskinesia in the Early Stage after Subthalamic Deep Brain Stimulation
Stereotactic and Functional Neurosurgery, 11/25/09
Relevance Score: 67%
The role of rehabilitation in deep brain stimulation of the subthalamic nucleus for Parkinson's disease: A pilot study
Parkinsonism & Related Disorders, 10/29/09
Relevance Score: 66%
A novel composite targeting method using high-field magnetic resonance imaging for subthalamic nucleus deep brain stimulation
Journal of Neurosurgery, 10/09/09
Relevance Score: 66%
Identification of the subthalamic nucleus in deep brain stimulation surgery with a novel wavelet-derived measure of neural background activity
Journal of Neurosurgery, 10/13/09
Relevance Score: 64%
Susceptibility-Enhanced 3-Tesla T1-Weighted Spoiled Gradient Echo of the Midbrain Nuclei for Guidance of Deep Brain Stimulation Implantation
Neurosurgery, 10/05/09
Relevance Score: 64%
Today in Movement Disorders...keeping you current
Receive free subspecialty "5-minute updates" via email
Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease
Brain, 12/07/09
Cognitive and Neuropsychiatric Profile of the Synucleinopathies: Parkinson Disease, Dementia With Lewy Bodies, and Multiple System Atrophy
Alzheimer Disease & Associated Disorders , 12/07/09
Acupuncture in the treatment of temporo-mandibular disorders in Sydenham's chorea patient: a case report
Acupuncture in Medicine, 12/07/09