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Treatment-Resistant Meningitis Leading To the Diagnosis of Currarino Syndrome: A Case Report
The Pediatric Infectious Disease Journal, 06/24/09

Kiefer AS et al. - A 20-day-old female infant developed fever. Sepsis evaluation revealed cerebrospinal fluid pleocytosis and a modestly decreased CSF glucose. After 48 hours of broad-spectrum antibiotics, the infant remained febrile. Repeat CSF analysis showed increased pleocytosis and a very low glucose value. Subsequently, a rectothecal fistula and sacral abnormalities were found, leading to the diagnosis of Currarino syndrome. Parameningeal foci should be considered in treatment-resistant meningitis.

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