Neurology Medical News about neuroprotective actions;androgens on motoneurons

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. 2008 Exclusive Survey—Earnings: Good news for primary care income

3. Medicare pay-for-reporting effort draws fire from frustrated doctors

4. Debunking Myths in the US Healthcare System

5. Doctors and the DEA Free full text

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Neuroprotective actions of androgens on motoneurons
Frontiers in Neuroendocrinology, 06/24/09

Fargo KN et al. – A review summarizes the protective and therapeutic effects of androgens in both central and peripheral nervous systems as specifically related to spinal and cranial motoneurons. Also presented are recent studies of how androgen treatment can interact with other treatment strategies to promote recovery from motoneuron injury.

Methods

Review of neuroprotective actions of androgens on motoneurons

Results

Androgens are critical for formation of important neuromuscular sex differences, decreasing magnitude of normally occurring cell death in select motoneuron populations
Throughout lifespan, androgens protect against motoneuron death due to axonal injury
Surviving motoneurons display regressive changes to their neurites from both direct axonal injury and loss of neighboring motoneurons
Androgen treatment enhances motoneuron ability to recover from regressive changes and to regenerate axons and dendrites, restoring normal neuromuscular function
Androgens exert protective effects via a variety of molecular pathways

<< Previous
Progesterone neuroprotection in traumatic CNS injury and...

Next >>
Combination treatment with progesterone and vitamin D hormone may...

Promising Novel Treatment For Human Cancer Chrysanthemum Indicum Extract
ScienceDaily, 10/19/09 Relevance Score: 64%

Potential Mechanisms Involved in the Prevention of Neurodegenerative Diseases by Lithium
CNS Neuroscience & Therapeutics, 11/11/09 Relevance Score: 63%

Development of an electronic pictorial asthma action plan and its use in primary care
Patient Education and Counselling, 11/03/09 Relevance Score: 45%

Potential neuroprotection mechanisms in PD: focus on dopamine agonist pramipexole
Current Medical Research and Opinion, 10/26/09 Relevance Score: 43%

Seriously Mentally Ill Women’s Safer Sex Behaviors and the Theory of Reasoned Action
Health Education & Behaviour, 10/06/09 Relevance Score: 43%