Your Article Summary
See Latest ArticlesNarcolepsy: Action of Two gamma-Aminobutyric Acid Type B Agonists, Baclofen and Sodium Oxybate
Pediatric Neurology , 06/23/09
Huang Y-S et al. - The dose of baclofen demonstrating an effect on nocturnal sleep without negative side effects was determined and maintained. Both drugs increased total sleep time and delta waves during sleep, but only sodium oxybate had an effect on daytime sleepiness and cataplexy at 3 months. Improvement of total nocturnal sleep time had no beneficial effect on daytime sleepiness. The mechanism by which sodium oxybate improves cataplexy and sleepiness is inferred to be due to properties beyond direct GABAB agonist action.
Related Articles
Anxiety and mood disorders in narcolepsy: a case-control study
General Hospital Psychiatry, 10/07/09
Relevance Score: 87%
A brain PET study in patients with narcolepsy-cataplexy
Journal of Neurology, Neurosurgery, and Psychiatry, 11/17/09
Relevance Score: 85%
Multiple sleep latency measures in narcolepsy and behaviourally induced insufficient sleep syndrome
Sleep Medicine, 11/16/09
Relevance Score: 82%
Mayo Clinic Proceedings Publishes Study of NUVIGIL in Patients with Shift Work Disorder
Cephalon, 11/03/09
Relevance Score: 80%
Today in Neuro/Psych pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Treatment with Olanzapine is Associated with Modulation of the Default Mode Network in Patients with Schizophrenia
Neuropsychopharmacology, 12/15/09
An investigation of the ability of elemene to pass through the blood-brain barrier and its effect on brain carcinomas
Journal of Pharmacy and Pharmacology, 12/15/09
Long-term levetiracetam treatment in patients with epilepsy: 3-year follow up
Acta Neurologica Scandinavica, 12/15/09
Today in Pediatric Neurology...keeping you current
Receive free subspecialty "5-minute updates" via email
Predicting school readiness from neurodevelopmental assessments at age 2 years after respiratory distress syndrome in infants born preterm
Developmental Medicine & Child Neurology, 12/15/09
Chronic inflammatory demyelinating polyradiculoneuropathy in children: characterized by subacute, predominantly motor dominant polyeuropathy with a favorable response to the treatment
Acta Neurologica Scandinavica, 12/15/09
Neurofibromatosis type 1 and high-grade tumors of the central nervous system
Child's Nervous System, 12/15/09
Today in Sleep...keeping you current
Receive free subspecialty "5-minute updates" via email
Protecting Sleep, Promoting Health in Later Life: A Randomized Clinical Trial
Psychosomatic Medicine, 12/15/09
Factors associated with short and long sleep
Preventive Medicine, 12/14/09
Acupuncture and reflexology for insomnia: a feasibility study
Acupuncture in Medicine, 12/11/09