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Narcolepsy: Action of Two gamma-Aminobutyric Acid Type B Agonists, Baclofen and Sodium Oxybate
Pediatric Neurology , 06/23/09
Huang Y-S et al. - The dose of baclofen demonstrating an effect on nocturnal sleep without negative side effects was determined and maintained. Both drugs increased total sleep time and delta waves during sleep, but only sodium oxybate had an effect on daytime sleepiness and cataplexy at 3 months. Improvement of total nocturnal sleep time had no beneficial effect on daytime sleepiness. The mechanism by which sodium oxybate improves cataplexy and sleepiness is inferred to be due to properties beyond direct GABAB agonist action.
Today in Neuro/Psych pharmacology...keeping you current
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Escitalopram and Venlafaxine for the Prophylaxis of Migraine Headache Without Mood Disorders
Clinical Neuropharmacology, 10/02/09
Nortriptyline and gabapentin, alone and in combination for neuropathic pain: a double-blind, randomised controlled crossover trial
The Lancet, 10/13/09
Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and Adolescents
JAMA, 10/29/09
Today in Pediatric Neurology...keeping you current
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Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and Adolescents
JAMA, 10/29/09
Risk factors for valproic acid resistance in childhood absence epilepsy
Seizure - European Journal of Epilepsy, 10/21/09
Intellectual Deficits in Children with ADHD Beyond Central Executive and Non-Executive Functions
Archives of Clinical Neurospsychology, 10/16/09
Today in Sleep...keeping you current
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Armodafinil for Treatment of Excessive Sleepiness Associated With Shift Work Disorder: A Randomized Controlled Study
Mayo Clinic Proceedings, 11/03/09
Validation of ECG-derived sleep architecture and ventilation in sleep apnea and chronic fatigue syndrome
Sleep and Breathing, 10/15/09
Review: continuous positive airway pressure devices are effective and cost-effective for obstructive sleep apnoea
Evidence-Based Medicine, 10/22/09
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