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See Latest ArticlesA pilot test of pioglitazone as an add-on in patients with relapsing remitting multiple sclerosis
Journal of Neuroimmunology, 06/24/09
Kaiser CC et al. - These results show that pioglitazone was well tolerated in RRMS patients with indications of beneficial effects, warranting further trials to establish clinical efficacy.
Douglas L. Feinstein, 06/24/09
| Further testing of this drug, or a related glitazone-type drug, in a larger group of MS patients is needed to confirm and expand upon these initial findings. If confirmed in a larger group of patients, this might prove useful as an adjunct treatment. Whether it would have any effect on other forms of MS is also not yet known. Other members of this class of drugs, the TZDs, are currently being tested by labs around the world, in other neurological diseases including AD, PD, ALS, and stroke. Our findings of possible neuroprotective effects might therefore be applicable to other neurological conditions and diseases. |
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Effect of glatiramer acetate on conversion to clinically definite multiple sclerosis in patients with clinically isolated syndrome (PreCISe study): a randomised, double-blind, placebo-controlled trial : The Lancet
The Lancet - Early Online Publication, 10/08/09
Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial
The Lancet Neurology, 10/16/09
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